Featured Publications
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Kuriyama R, Mullins JM, Skop AR. The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential. Mol Biol Cell. 2025 Jul 1;36(7):re4. doi: 10.1091/mbc.E25-03-0120. Epub 2025 May 28. PMID: 40434898; PMCID: PMC12260166.
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Skop, A., Qing, C. X., Rauf, H., Chu, D. (2025). Lab culture: A recipe for innovation in science. Self-published. April 17th, 2025
Science meets the kitchen in this unique cookbook that brings the brilliance of the lab to your table!
Step into the flavorful world of Lab Culture Recipes, an extraordinary cookbook and community where science and cooking unite to celebrate global cultures and innovation. This unique collection, curated by scientists from across the globe, blends culinary heritage with scientific creativity, offering recipes that bridge the lab and the kitchen. Lab Culture Recipes is more than just a cookbook—it's a celebration of diversity and connection. Inspired by lively dinners among scientists, this initiative highlights the personal stories, favorite foods, and cultural traditions of researchers worldwide. These shared meals have sparked laughter, collaborations, and groundbreaking ideas, demonstrating how food can bring people together in meaningful ways. The cookbook features a wide array of dishes that cater to every palate. From comforting classics like Granny’s Corny Cornbread to adventurous delights such as Not Your Granny’s Peach Cobbler, every recipe is infused with a scientist's personal touch. Explore international favorites like Moroccan Lentil Soup by Megumi Fuse, Feuilleté au Fromage by Alexandra Naba, Palak Paneer by Swathi Arur, and decadent treats such as Chocolate Bomb with Raspberries by Jagan Srinivasan or Melomakarona by Irini Topalidou. Each dish is a testament to the intersection of science, culture, and culinary artistry. Beyond recipes, Lab Culture Recipes invites readers to discover what scientists eat for breakfast or snack on during busy days in the lab. It also delves into their dream dinner companions—offering a glimpse into the human side of scientific minds. This innovative approach humanizes scientists by showcasing their passions outside the lab while emphasizing how diverse backgrounds enrich scientific progress. In this kitchen, experimentation is always encouraged. Whether you're a seasoned cook or a curious beginner, Lab Culture Recipes inspires creativity and connection through food. Visit labculturerecipes.com to explore this vibrant community and bring the brilliance of the lab to your table. |
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Patel SA, Park S, Zhu D, Torr EE, Dureke AG, McIntyre A, Muzyka N, Severson J, Skop AR. (2024)Extracellular vesicles, including large translating vesicles called midbody remnants, are released during the cell cycle. Mol Biol Cell. 2024 Nov 13:mbcE23100384. doi: 10.1091/mbc.E23-10-0384. Epub ahead of print. PMID: 39535882.
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Murray SA, Holzbaur ELF, Munson M, Cimini D, Lane TF, Alvania R, Applewhite DA, Chang F, Chen EH, Earnshaw WC, Evans CS, Li R, Mierzwa BE, Oliver T, Segarra VA, Skop AR, Weaver LN, Asai DJ, Boyce M, Zavala ME, Hammonds-Odie L, Vigoreaux J. (2024) ASCB statement of commitment to diversity, equity, and inclusion. Mol Biol Cell. (2024) Aug 1;35(8):ed3. doi: 10.1091/mbc.E24-06-0244. PMID: 39037589.
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Skop, A., Schindler, K. Localized translation in the embryo. Nat Rev Mol Cell Biol (2024). doi: https://doi.org/10.1038/s41580-024-00725-z
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Patel, S, Park S., Torr, E., Dureke, AG, McIntyre, A, Skop, AR. (2023). A protocol for the isolation of large extracellular vesicles or midbody remnants from human cell culture medium using 1.5% PEG 6000 and gold nanoparticles and MKLP1 as a marker. CellSTAR protocols, Volume 4, Issue 4, 15 December 2023 doi: https://doi.org/10.1016/j.xpro.2023.10256
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Jung, GI, Londono-Vasquez, D., Park, S., Skop, AR., Balboula, A., Schindler, K. (2023). A meiotic midbody structure in mouse oocytes acts as a barrier for nascent translation to ensure developmental competence. Nature Communications, doi: https://doi.org/10.1101/2022.11.17.516899
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Park, S., Dahn, RD, Kurt, E., Presle, A, VanDenHeuvel, K., Moravec, C., Jambhekar, A., Olukoga, O., Shepherd, J., Echard, A., Blower, MD., Skop, AR (2023). The midbody and midbody remnant are assembly sites for RNA and active translation. Developmental Cell, Aug 1:S1534-5807(23)00357-X. doi: 10.1016/j.devcel.2023.07.009. Online ahead of print. PMID: 37552987
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Skop, A. R., Kurt, E., & Marks, C. (2020). Genetic reflections: A coloring book. Independently published
Genetic Reflections - A Coloring Book aims to inspire young students and the public to explore the beauty of science and genetics. The organisms in this book are considered ‘model’ organisms, as they are widely studied in laboratories with hopes to understand human biology, disease pathologies, and ways to improve agricultural crops. Despite the great differences in shape and size, on the genetic level there are lots of similarities.In every species, DNA sequences consist of the same four building blocks (G, C, A, and T). However, slight changes in their use, even in the same gene, can occur in each species. The way our bodies and cells work are well conserved throughout evolution, even in species that may look very different from us. The beauty of our world, even on the cellular level, is apparent.Genetic Reflections - A Coloring Book is a collaboration between Ahna Skop, Elif Kurt and Caitlin Marks; two UW-Madison undergraduate Skop Lab members. This coloring book is the outcome of a year-long independent study in Life Sciences Communication with goals to broadly disseminate the Genetic Reflections scientific glass art installation created by Angela Johnson and Ahna Skop.Part of the proceeds of this book will be donated to charities and programs that support STEAM (Science, Technology, Engineering, Arts, and Mathematics) educational innovations or public outreach events.
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Del Castillo U, Gnazzo MM, Sorensen Turpin CG, Nguyen KCQ, Semaya E, Lam Y, de Cruz MA, Bembenek JN, Hall DH, Riggs B, Gelfand VI, Skop AR. Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics. Traffic. 2019,Jun;20(6):436-447. doi: 10.1111/tra.12647. Epub 2019 May 8. PubMed PMID:30989774; PubMed Central PMCID: PMC6553494.
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Billmyre KK, Doebley AL, Spichal M, Heestand B, Belicard T, Sato-Carlton A,Flibotte S, Simon M, Gnazzo M, Skop A, Moerman D, Carlton PM, Sarkies P, Ahmed S.The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing. PLoS Genet. 2019 Mar 28;15(3):e1008004. doi:10.1371/journal.pgen.1008004. eCollection 2019 Mar. PubMed PMID: 30921322; PubMed Central PMCID: PMC6456222.
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Gnazzo MM, Uhlemann EE, Villarreal AR, Shirayama M, Dominguez EG, Skop AR. The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4. Mol Biol Cell. 2016 Oct 15;27(20):3052-3064. Epub 2016 Aug 24. PubMed PMID: 27559134;PubMed Central PMCID: PMC5063614.
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Gnazzo MM, Skop AR. Spindlegate: the biological consequences of disrupting traffic. Dev Cell. 2014 Mar 10;28(5):480-2. doi:10.1016/j.devcel.2014.02.014. PubMed PMID: 24636255.
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Bonner MK, Han BH, Skop A. Profiling of the mammalian mitotic spindle proteome reveals an ER protein, OSTD-1, as being necessary for cell division and ER morphology. PLoS One. 2013 Oct 10;8(10):e77051. doi:10.1371/journal.pone.0077051. eCollection 2013. Erratum in: PLoS One. 2017 Jan 30;12 (1):e0171399. PubMed PMID: 24130834; PubMed Central PMCID:PMC3794981.
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Pittman KJ, Skop AR. Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow in Caenorhabditis elegans. Cytoskeleton (Hoboken). 2012 Oct;69(10):826-39. doi: 10.1002/cm.21053. Epub 2012 Aug 10. PubMed PMID: 22887994; PubMed Central PMCID: PMC3650724.
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Shivas JM, Skop AR. Arp2/3 mediates early endosome dynamics necessary for the maintenance of PAR asymmetry in Caenorhabditis elegans. Mol Biol Cell. 2012 May;23(10):1917-27. doi: 10.1091/mbc.E12-01-0006. Epub 2012 Mar 28. PubMed PMID: 22456506; PubMed Central PMCID: PMC3350555.
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Ai E, Poole DS, Skop AR. Long astral microtubules and RACK-1 stabilize polarity domains during maintenance phase in Caenorhabditis elegans embryos. PLoS One. 2011 Apr 20;6(4):e19020. doi: 10.1371/journal.pone.0019020. PubMed PMID:21533050; PubMed Central PMCID: PMC3080402.
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Bonner MK, Poole DS, Xu T, Sarkeshik A, Yates JR 3rd, Skop AR. Mitotic spindle proteomics in Chinese hamster ovary cells. PLoS One. 2011;6(5):e20489.doi: 10.1371/journal.pone.0020489. Epub 2011 May 27. PubMed PMID: 21647379;PubMed Central PMCID: PMC3103581.
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Shivas JM, Morrison HA, Bilder D, Skop AR. Polarity and endocytosis:reciprocal regulation. Trends Cell Biol. 2010 Aug;20(8):445-52. doi:10.1016/j.tcb.2010.04.003. Epub 2010 May 20. Review. PubMed PMID: 20493706;PubMed Central PMCID: PMC2917511.
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Ai E, Skop AR. Endosomal recycling regulation during cytokinesis. Commun Integr Biol. 2009 Sep;2(5):444-7. PubMed PMID: 19907714; PubMed Central PMCID:PMC2775247.
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Nakayama Y, Shivas JM, Poole DS, Squirrell JM, Kulkoski JM, Schleede JB, Skop AR. Dynamin participates in the maintenance of anterior polarity in the Caenorhabditis elegans embryo. Dev Cell. 2009 Jun;16(6):889-900. doi:10.1016/j.devcel.2009.04.009. PubMed PMID: 19531359; PubMed Central PMCID:PMC2719978.
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Ai E, Poole DS, Skop AR. RACK-1 directs dynactin-dependent RAB-11 endosomal recycling during mitosis in Caenorhabditis elegans. Mol Biol Cell. 2009 Mar;20(6):1629-38. doi: 10.1091/mbc.E08-09-0917. Epub 2009 Jan 21. Erratum in:Mol Biol Cell. 2009 Dec;20(23):5036. PubMed PMID: 19158384; PubMed Central PMCID:PMC2655251.
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Bonner MK, Skop AR. Cell division screens and dynamin. Biochem Soc Trans. 2008 Jun;36(Pt 3):431-5. doi: 10.1042/BST0360431. Review. PubMed PMID: 18481974; PubMed Central PMCID: PMC3660067.
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Zhang H, Skop AR, White JG. Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos. J Cell Sci. 2008, Jan 15;121(Pt 2):155-61. doi: 10.1242/jcs.015966. PubMed PMID: 18187449.
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Dinkelmann MV, Zhang H, Skop AR, White JG. SPD-3 is required for spindle alignment in Caenorhabditis elegans embryos and localizes to mitochondria. Genetics. 2007 Nov;177(3):1609-20. Epub 2007 Oct 18. PubMed PMID: 17947426;PubMed Central PMCID: PMC2147968.
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Konopka CA, Schleede JB, Skop AR, Bednarek SY. Dynamin and cytokinesis.Traffic. 2006 Mar;7(3):239-47. Review. PubMed PMID: 16497219; PubMed Central PMCID: PMC3654675.
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Otegui MS, Verbrugghe KJ, Skop AR. Midbodies and phragmoplasts: analogous structures involved in cytokinesis. Trends Cell Biol. 2005 Aug;15(8):404-13.Review. Erratum in: Trends Cell Biol. 2005 Oct;15(10):517. PubMed PMID: 16009554;PubMed Central PMCID: PMC3677513.
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Skop AR, Liu H, Yates J 3rd, Meyer BJ, Heald R. Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science. 2004 Jul 2;305(5680):61-6. Epub 2004 May 27. PubMed PMID: 15166316; PubMed Central PMCID: PMC3679889.
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Thompson HM, Skop AR, Euteneuer U, Meyer BJ, McNiven MA. The large GTPase dynamin associates with the spindle midzone and is required for cytokinesis. Curr Biol. 2002 Dec 23;12(24):2111-7. PubMed PMID: 12498685; PubMed Central PMCID:PMC3690653.
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Skop AR, Bergmann D, Mohler WA, White JG. Completion of cytokinesis in C.elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex. Curr Biol. 2001 May 15;11(10):735-46. PubMed PMID: 11378383; PubMed Central PMCID: PMC3733387.
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Skop AR, White JG. The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr Biol. 1998 Oct8;8(20):1110-6. PubMed PMID: 9778526; PubMed Central PMCID: PMC3690630.
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